All eight babies born in what is believed to be only the second case of octuplets surviving more than a few hours are stable and continue to do well, doctors have said.
The six boys and two girls were delivered on Monday at the Kaiser Permanente Bellflower Medical Centre in Los Angeles.
Initially two of the newborns were put on ventilators. But one of the doctors involved confirmed that they were now all breathing on their own.
Dr Mandhir Gupta said the eight babies "are doing actually very, very well". He added: "Only three babies need some sort of oxygen through the nose right now but they are breathing on their own."
The octuplets were born nine weeks premature to a mother who has not been named. They weighed between 1lb 8oz and 3lb 4oz and were delivered by Caesarean section within five minutes.
Doctors and the babies' parents had been expecting seven babies, with the eighth coming as a surprise. All of the babies - dubbed with the letters A to H - are expected to remain in hospital for at least two months.
The babies' mother checked into the hospital during her 23rd week of pregnancy, giving birth seven weeks later. Hospital officials have not said if she was on fertility drugs.
Records show that the world's first live octuplets were born in March 1967 in Mexico City, but all died within 14 hours of the birth. In 1998, octuplets were born to a mother in Houston, Texas. The smallest died a week after the birth. But the seven other siblings survived and turned age 10 in December.
Their Nigerian-born parents, Nkem Chukwu and Iyke Louis Udobi, gave their best wishes to the parents involved in the latest multiple birth.
"It's a blessing, truly a blessing. We'll keep praying for them," said Nkem Chukwu.
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